For Ascariasis, which of the following is a first line treatment?

Albendazole is considered the first-line treatment for Ascariasis, which is an intestinal infection caused by the Ascaris lumbricoides worm. The medication works by inhibiting the polymerization of tubulin, leading to paralysis and death of the helminth. This facilitates the worm's expulsion from the intestine through natural gut motility.

In the context of treatment for Ascariasis, Albendazole is preferred because it effectively reduces the number of adult worms in the intestine and has a well-established safety profile. Furthermore, it is generally well-tolerated and provides a single-dose treatment option for many patients, making it practical for widespread use in endemic regions.

Other options listed offer treatments for different infections. Metronidazole is mainly effective against anaerobic bacteria and protozoa, such as Giardia and Trichomonas, and is not effective for helminthic infections like Ascariasis. Ivermectin is used primarily for conditions such as Strongyloidiasis and Onchocerciasis, not specifically for Ascaris. Rifampin is an antibiotic used to treat tuberculosis and certain bacterial infections, rather than helminthic diseases.

Therefore, the preference for Albendazole in treating Ascariasis stems