What is the first line treatment for HSV Encephalitis?

The first-line treatment for HSV (Herpes Simplex Virus) Encephalitis is IV Acyclovir. Administering IV Acyclovir is essential because it provides high concentrations of the antiviral medication directly into the bloodstream, allowing for rapid and effective management of the viral infection affecting the central nervous system. This treatment is particularly critical considering the potential for the infection to cause significant neurological damage and the rapid onset of serious symptoms associated with HSV encephalitis.

Acyclovir works by inhibiting viral DNA synthesis, effectively reducing the viral load and preventing further progression of the disease. The intravenous route is preferred in cases of severe infections or when central nervous system involvement is suspected or confirmed, as it facilitates faster absorption and higher drug levels compared to oral administration.

In addition to antiviral therapy, patients often require supportive care for various symptoms that arise due to the encephalitis, but the use of IV Acyclovir remains the cornerstone of treatment for this serious condition.