What is the first line treatment for Sepsis?

The first-line treatment for sepsis is indeed the combination of intravenous fluids and broad-spectrum antibiotics. When a patient is diagnosed with sepsis, it is critical to address the infection promptly and effectively while also managing the patient's hemodynamic instability, which often accompanies this condition.

Administering intravenous fluids helps to restore and maintain adequate circulation volume and improve tissue perfusion, which is essential for preventing organ dysfunction and supporting the body's response to infection. The general recommendation is to provide approximately 30 mL/kg of crystalloids within the first three hours after sepsis identification.

Simultaneously, initiating broad-spectrum antibiotics is vital, as sepsis is often the result of a bacterial infection, and timely antibiotic therapy can significantly reduce morbidity and mortality rates. The choice of broad-spectrum antibiotics should be guided by local guidelines and susceptibility patterns, ensuring that any potential pathogens are effectively targeted.

While vasopressors can be a part of the management strategy, particularly if the patient remains hypotensive despite fluid resuscitation, they are not first-line treatment options on their own. Instead, their use generally follows initial fluid resuscitation efforts. Immediate surgery may be necessary for some source control in cases such as intra-abdominal infections or abscesses but is not a