What is the first line treatment for Tinea Corporis/Pedis/Cruris?

The first line treatment for Tinea Corporis, Tinea Pedis, and Tinea Cruris is topical antifungals, such as Clotrimazole or Terbinafine. This approach is effective due to the superficial nature of the infections, which are caused by dermatophyte fungi that primarily affect the outer layers of the skin. Topical fungicides directly target the site of infection, generally leading to quicker resolution of symptoms and fungal clearance.

Topical antifungals work by disrupting the fungal cell membrane or inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby effectively killing the fungus or preventing its growth. Clotrimazole and Terbinafine are commonly recommended because they have a favorable safety profile, are generally well tolerated, and are available in forms like creams and powders that can be easily applied to affected areas.

Using systemic antifungals, such as oral fluconazole, is typically reserved for more extensive infections or cases where topical treatment fails, as these medications can have broader side effects and require monitoring. Topical corticosteroids, while they can reduce inflammation, do not target the underlying fungal infection and may exacerbate the condition by allowing the fungus to spread if used inappropriately.