What is the most appropriate first line treatment for intertrigo due to candidiasis?

The most appropriate first line treatment for intertrigo due to candidiasis is the combination of topical azoles and keeping the affected area dry. Intertrigo is an inflammatory condition that occurs in skin folds and is often exacerbated by warmth, moisture, and friction, which makes it a perfect environment for Candida species to thrive.

Topical azoles, such as clotrimazole or miconazole, effectively target the fungal component of the infection by inhibiting ergosterol synthesis, a vital component of the fungal cell membrane. This antifungal action helps to reduce the Candida population and alleviate the symptoms associated with intertrigo.

In addition to the antifungal treatment, maintaining dryness in the affected area is crucial. This can be achieved through the use of absorbent powders or barrier creams, which help to minimize moisture and reduce friction, thereby preventing further irritation and exacerbation of the infection.

Other options, like Amphotericin B, are primarily reserved for severe systemic fungal infections due to their potency and side effects. Itraconazole is an oral antifungal that might be used for different clinical scenarios but is not the first-line treatment for localized skin infections like candidiasis in intertrigo. Clotrimazole troches are designed for oral thr